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課程名稱 |
臨床影像學二
Fundamentals of Medical Imaging(Ⅱ) |
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開課學期 |
111-2 |
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授課對象 |
學程 神經生物與認知科學學程 |
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授課教師 |
湯佩芳 |
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課號 |
PT4038 |
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課程識別碼 |
408 43340 |
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班次 |
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學分 |
1.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三9(16:30~17:20) |
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上課地點 |
物治實習4F |
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備註 |
本課程中文授課,使用英文教科書。與邱銘章、鄭建興、彭信逢、周弘傑、陳達夫、陳雅芳、賴達明、林靜嫻、湯頌君、吳文超合授
限本系所學生(含輔系、雙修生)
總人數上限：45人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
本課程為物理治療學系六年學制學生之必修課程，課程內容為成人與小兒常見神經內外科疾病之神經、血管臨床影像判讀，以養成物理治療核心專業能力。內容主要涵蓋﹕(一)神經發展與神經解剖學概觀;(二)電腦斷層(含電腦斷層灌流)造影、磁振造影、血管攝影、正子攝影、神經科超音波、新生兒超音波與等影像成像原理與臨床應用之介紹;(三)正常與異常影像判讀原則;(四)主要成人與小兒神經內外科疾病(含缺血與出血性腦中風、腦白質病變、多發性硬化症、腦部感染、頭部外傷、水腦、腦腫瘤、巴金森氏症、失智症、脊髓損傷、脊髓腫瘤與病變、周產期腦病變、早產常見腦部病變、腦性麻痺、腦先天畸形、兒童中風、遺傳性腦疾病等)之神經影像判讀、神經科超音波、與新生兒超音波影像判讀。
本課程採多元學習方式進行，除授課教師講授相關知識之外，亦包含文獻閱讀、討論、報告、與問題導向學習(PBL)等學習活動，以培養學生專業能力、批判思考、終身學習、和跨領域溝通以及團隊合作能力。 |
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課程目標 |
修習學生在結束本課程後，應能：
1. 瞭解電腦斷層、磁振造影、血管攝影、正子攝影、與神經超音波等之影像原理；
2. 瞭解如何判讀正常之腦部與脊髓電腦斷層、磁振造影、血管攝影、正子攝影等影像；
3. 瞭解如何判讀神經超音波影像；
4. 瞭解如何判讀主要成人及小兒神經內外科疾病之神經影像、血管攝影、與神經超音波影像，並理解醫師的判讀報告；
5. 瞭解神經影像、血管攝影、與神經超音波影像資訊與臨床表徵間的關係；
6. 瞭解如何運用神經影像、血管影像、與神經超音波影像資訊於成人神經物理治療及小兒物理治療之臨床決策。 |
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課程要求 |
先修科目: 機能解剖學 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 備註： 需事先與授課老師預約 |
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指定閱讀 |
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參考書目 |
I. Neuroscience textbooks
A. Bear M, Connors B, Paradiso M. Neuroscience: Exploring the Brain. 3rd ed. [E-book] Baltimore: Lippincott Williams & Wilkins. 2016.
B. Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia A-S, Mooney RD, Platt ML, White LE. (2018) Neuroscience. 6th ed. Sunderland, MA, USA: Sinaur Associates, Inc.
C. Lundy-Ekman L. Neuroscience Fundamentals for Rehabilitation. 5th ed. St. Louis: Saunders Elsevier; 2018
D. https://nba.uth.tmc.edu/neuroscience/index.htm (Neuroanatomy Online)
II. Neuroanatomy textbooks
A. Haines DE. Neuroanatomy: An Atlas of Structures, Sections, and Systems. 9th Ed. Philadelphia: Wolters Kluwer. 2015.
B. Haines DE. Neuroanatomy Atlas in Clinical Context: Structures, Sections, and Systems. 10th Ed. Philadelphia: Wolters Kluwer. 2019.
C. Kiernan JA, Rajakumar N. Barr’s The Human Nervous System: An Anatomical Viewpoint. 10th Ed. Philadelphia: Wolters Kluwer Lippincott Williams & Wilkins, 2014.
D. Mai JK and Paxinos G. The Human Nervous System [E-book]. 3rd Ed. Burlington: Elsevier Science, 2012
E. Mai JK, Paxinos G, Voss T. Atlas of the Human Brain. 3rd Ed. New York: Academic Press. 2008.
F. Martin J. (Ed.) Neuroanatomy: Text and Atlas. [E-book]. 5th ed. McGraw Hill. 2021
G. Vanderah, TW. Nolte’s the Human Brain: An Introduction to Its Functional Anatomy [E-book]. 7th ed. Philadelphia, PA: Elsevier. 2016.
III. Neuroimaging textbooks
A. Agarwal N. and Port J. D. (Eds.) Neuroimaging: Anatomy Meets Function (1st. Ed.) E-book]. Cham, Springer International Publishing. 2018.
B. Cho ZH (Ed.). 7.0 Tesla MRI Brain Atlas: In-vivo atlas with cryomacrotome correlation (2nd Ed.) [E-book]. Berlin, Heidelberg: Springer. 2015.
C. Gillard JH, Waldman AD, and Barker PB. (Eds.). Clinical MR Neuroimaging: Physiological and Functional Techniques (2nd ed). New York: Cambridge University Press. 2010.
D. Naidich TP. Duvernoy's Atlas of the Human Brain Stem and Cerebellum [E-book]: High-field MRI: Surface Anatomy, Internal Structure, Vascularization and 3D Sectional Anatomy. Vienna: Springer Vienna. 2009.
E. Sanelli PC et al. Neuroimaging: the Essentials. Philadelphia: Wolters Kluwer. 2016.
F. Scarobino T, Pollice S (Editors). Imaging spine after treatment: A case-based Atlas. [E-book]. Milan: Springer Milan. 2014
G. Scarobino T, Pollice S, Popolizio T (Editors). High Field Brain MRI: Use in Clinical Practice (2nd Ed.) [E-book]. Cham: Springer International Publishing. 2017.
H. Scott W. Atlas (Editor). Magnetic Resonance Imaging of the Brain and Spine [E-book]. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2017.
I. 陳煥武編譯(Catherine Westbrook原著)。圖解核磁共振造影學。台北市:合記。2006。
IV. Other readings: to be determined by instructors
A. Basic principles of imaging:
1. Goldman LW. Principles of CT and CT technology. J Nucl Med Technol 2007;35:115-128; quiz 129-130.
2. Currie S, Hoggard N, Craven IJ, Hadjivassiliou M, Wilkinson ID. Understanding MRI: basic MR physics for physicians. Postgrad Med J 2013;89:209-223.
3. Townsend DW. Physical principles and technology of clinical PET imaging. Ann Acad Med Singapore 2004;33:133-145.
4. 郭盈昇(Ying-Sheng Kuo)、陳啟仁(Chi-Jen Chen)、王宣惠(Hsuan-Hei Wang)、關婉君(Wan-Chun Kuan)、蔡承坤(Cheng-Kun Tsai)、邱文達(Wen-Ta Chiu)。磁振造影於中樞神經系統之運用(The Applications of MRI in Central Nervous System)。科儀新知; 2011; 180期: P4 - 17。
5. 胡漢華。神經科超音波。中華民國醫用超音波學會會訊。2013:9/10月。
6. 周弘傑。新生兒科腦部超音波。中華民國醫用超音波學會會訊。2013:11/12月。
B. Aging brain:
1. Jagust W, D’Esposito M. Imaging the Aging Brain [E-book]. Oxford Scholarship Online. 2009.
2. Rizzo M, Anderson S, Fritzsch B. (Eds.). The Wiley Handbook on the Aging Mind and Brain. [E-book]. Hoboken, NJ: Wiley, 2018.
C. Pediatric neuroimaging :
1. Barkovich, A. J. and Raybaud, C. Pediatric Neuroimaging (5th Ed.) [E-book]. Philadelphia : Wolters Kluwer Health/Lippincott Williams & Wilkins. 2012.
2. Barkovich MJ, Barkovich AJ. MR Imaging of Normal Brain Development. Neuroimaging Clin N Am 2019;29:325-337.
3. Barkovich AJ. Imaging of the Newborn Brain. Semin Pediatr Neurol 2019;32:100766.
4. Edwards TJ, Sherr EH, Barkovich AJ, Richards LJ. Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes. Brain 2014;137:1579-1613.
5. Doherty D, Millen KJ, Barkovich AJ. Midbrain and hindbrain malformations: advances in clinical diagnosis, imaging, and genetics. Lancet Neurol 2013;12:381-393.
6. Glenn OA, Cuneo AA, Barkovich AJ, Hashemi Z, Bartha AI, Xu D. Malformations of cortical development: diagnostic accuracy of fetal MR imaging. Radiology 2012;263:843-855.
D. Stroke:
1. Campbell BC, Parsons MW. Imaging selection for acute stroke intervention. Int J Stroke 2018;13:554-567.
2. Kamalian S, Lev MH. Stroke Imaging. Radiol Clin North Am 2019;57:717-732.
3. Vilela P, Rowley HA. Brain ischemia: CT and MRI techniques in acute ischemic stroke. Eur J Radiol 2017;96:162-172.
V. Useful on-line learning resources
A. https://learnneuroradiology.com/
B. https://radiologyassistant.nl/neuroradiology/
C. https://radiopaedia.org
D. https://www.med.harvard.edu/aanlib/
E. https://www.mr-tip.com/
F. https://www.mrisafety.com/lectures.asp
G. https://www.thehumanbrain.net/
H. http://www.thehumanbrain.info/mri/mr-navigator.php |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
平時成績 |
20% |
上課參與(6 %)、提問及討論(6 %)、2/22小考與作業(8 %)
* 請假都請於課前(除病假外)在學校請假系統提出申請並附證明。未能做到時皆以曠課論，按比例扣平時成績。
* 隨台灣大學校隊出隊比賽的運動防護公假:每位同學整學期只會被批准一次。 |
2. |
課堂報告 |
10% |
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3. |
期中考 |
30% |
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4. |
期末考 |
40% |
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針對學生困難提供學生調整方式 |
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上課形式 |
以錄音輔助, 以錄影輔助, 提供學生彈性出席課程方式 |
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作業繳交方式 |
延長作業繳交期限 |
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考試形式 |
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其他 |
由師生雙方議定 |
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週次 |
日期 |
單元主題 |
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第1週 |
2023/2/22 |
湯佩芳老師
Course overview and Quiz on neuroanatomy
Introduction to on-line neuroimage resources (in-class practice) |
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第2週 |
2023/3/1 |
吳文超老師
Introduction to medical imaging: CT (non-contrast, contrast, perfusion, angiography), MRI (basic structure, diffusion, susceptibility, angiography, perfusion, and spectroscopy), and PET (PET CT) |
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第3週 |
2023/3/8 |
湯佩芳老師
Use of neuroimaging in neurorehabilitation: Student presentations of readings and discussions (3 groups) |
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第4週 |
2023/3/15 |
陳雅芳醫師
General principles of image reading and imaging in cerebrovascular disorders |
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第5週 |
2023/3/22 |
鄭建興醫師
Neuroimaging in acute ischemic stroke |
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第6週 |
2023/3/29 |
賴達明醫師
Neuroimaging in cerebral hemorrhage, hydrocephalus, traumatic brain injury, and spinal disorders
(可能延後一小時開始上課) |
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第7週 |
2023/4/5 |
民族掃墓節放假 |
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第8週 |
2023/4/12 |
Midterm exam |
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第9週 |
2023/4/19 |
陳雅芳醫師
Neuroimaging in white matter lesions, MS, & infection |
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第10週 |
2023/4/26 |
吳文超老師
Neuroimaging in brain tumors |
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第11週 |
2023/5/3 |
陳達夫醫師
Neuroimaging in normal aging and dementia
(可能延後一小時開始上課) |
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第12週 |
20203/5/10 |
林靜嫻醫師
Neuroimaging in Parkinson’s disease and other basal ganglia disorders |
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第13週 |
2023/5/17 |
湯頌君醫師
Ultrasonic imaging in adult neurological disorders |
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第14週 |
2023/5/24 |
周弘傑醫師
Neonatal brain ultrasonic imaging |
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第15週 |
2023/5/31 |
彭信逢醫師
Pediatric neuroimaging: congenital abnormalities, vascular injuries, traumatic injuries, metabolic/toxic disorders, infection |
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第16週 |
2023/6/7 |
湯佩芳老師
Final Exam |
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